ABSTRACT
High erythrocyte sedimentation rate and D-dimer were also observed.15 The main pathogenesis of COVID-19 infection as a respiratory system targeting virus was severe pneumonia, RNA anaemia, combined with the incidence of ground-glass opacities, and acute cardiac injury. The comparable viral load in a group of asymptomatic carriers of COVID-19 was higher than that of the symptomatic carriers and increasing level of white blood cell count (12.4×109/L), neutrophil count (7.82×109/L), C-reactive protein level (189.2mg/L), low lymphocyte count (0.84×109/L) and platelet count (88×109/L) was found different than the normal range in asymptomatic patients.22 2.1 Clinical Evaluation of Asymptomatic Carriers: Many asymptomatic persons were actually a source of SARS-CoV-2 infection but were considered healthy before they underwent screening. CRP levels, LDH levels, and white blood cell counts were elevated occurred in 10, 13 and 1 patient, respectively.24 According to the study, asymptomatic infection was seldom seen in young people;the proportion with severe COVID-19 was low, and the proportion with ordinary COVID-19 was high. 2.3 Evaluation of Asymptomatic and Symptomatic Carriers: Table-1: Description of general characteristics responsible for evaluation of asymptomatic carriers of Covid-19. General characteristics Asymptomatic Carriers Symptomatic Carriers Normal range White blood cell count (× 10⁹ cells per L) 5.65 9.43 4.00–10.00 Neutrophil count (× 10⁹ cells per L) 3.62 8.21 1.80–6.30 Lymphocyte count (× 10⁹ cells per L) 1.55 0.69 1.10–3.20 C-reactive protein (mg/L) 0.69 202.03 0.0–5.0 3 Prophylactic Regimens for Prevention from Sars Cov-II Virus: This review aims to interrogate the current evidence base, and present the potential immune-mediating, antioxidant, and antimicrobial roles of vitamins A to E in the context of respiratory disease, and to extrapolate this evidence to evaluate the potential roles in the fight against COVID-19.
ABSTRACT
The Coronavirus Disease 2019 (COVID-19) is caused by severe acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection Attack mainly on the immune system of the body. The herbs like holy basil, cinnamon, ginger, black pepper are highly available, accessible and widely used in the kitchen and are convenient to educate and train about its use to community health workers, community and even to all public that they can have cost effective treatment with herbal home remedies. Zinc highly important for adequate T cell differentiation, and this observed is triggered by long-lasting changes in intracellular zinc levels due to induction of regulatory T cells (Treg) cells and dampening of pro-inflammatory Th17 and Th9 cells.5 * Zn Can Directly Inhibit SARS-CoV-2 Replication: Using recombinant SARS-CoV nsp12, that Zn2+ directly inhibited the in vitro RdRp activity. Earlier, it was also shown that Zn2+ inhibited the proteolytic processing of replicase polyprotein.6 Increasing concentration of intracellular zinc inhibits the replication of SARS coronavirus (SARS-CoV) and other viruses.7 Viral RNA-dependent RNA polymerase (RdRp) are suitable targets for novel antiviral drugs, since their activity is strictly virus-specific and may be blocked without severely affecting key cellular functions.